Building web-based medical record systems to support the management of Multi-Drug Resistant Tuberculosis in developing countries including Peru and Haiti and also Russia.

Decision support and clinican reporting tools for real time surveillance of disease outbreaks

Telemedicine

Developing techniques for low-cost store and forward telemedicine in developing countries. 
Evaluating the effectiveness and practicality of such techniques.

Decision support systems

Developing tools to assist in the diagnosis and management of heart disease.

Performing a clinical evaluation of a cardiology decision support system "the Heart Disease Program"
 

Informatics Program, Children's Hospital, Boston
The Program in Infectious Disease and Social Change, Dept. of Social Medicine, Harvard Medical School
Clinical Decision Making Group, Laboratory for Computer Science, Massachusetts Institute of Technology
 

 Hamish S F Fraser, Isaac S Kohane, William J Long. 
 Using the Technology of the World Wide Web to Manage Clinical Information 
 British Medical Journal, No 7094 Volume 314 Saturday 31 May 1997 P 1600-4
 http://www.bmj.com/archive/7094ip1.htm

 Hamish S F Fraser, William J Long, Shapur Naimi.
 Differential Diagnoses of the Heart Disease Program have better Sensitivity than Resident Physicians.
 AMIA Fall Symposium on Computer Applications in Health Care, 1998 November 7-11. Orlando, Florida; Hanley and Belfus; 1998, p  622-26

 Hamish Fraser, St John D McGrath
 Information Technology and Telemedicine in Sub-Saharan Africa (Editorial)
 BMJ. 2000 Aug 19-26;321(7259):465-6

 Hamish S F Fraser, William J Long, Shapur Naimi
 New Approaches to Measuring the Performance of Programs that Generate Differential Diagnoses using ROC Curves and Other Metrics.
 Proc AMIA Symp. 2000;:255-9.

 Fraser HS, Jazayeri D, Bannach L, Szolovits P, McGrath SJ.
 Telemedmail: free software to facilitate telemedicine in developing countries.
 Medinfo. 2001;10(Pt 1):815-9.

Hamish SF Fraser
Clinical information and decision-support systems
Chapter 3.2, Medicine and the Internet (Third Edition)
Bruce McKenzie Editor
Oxford University Press 2002

The Gates Foundation through a grant to the Program in Infectious Disease and Social Change, Dept. of Social Medicine, Harvard Medical School to treat Multi-drug resistant TB in Peru.

The Fogarty International Center of the NIH, International Training Program in Medical Informatics, Faculty Member

2000-2002. Agency for Health Care Quality and Research. Biodefense, Automated Decision Support and Clinical Data. 

Previously Funded Efforts

1995 -- 1997    NIH/NHLBI   “Clinical Evaluation of the Heart Disease Program”
1998 -- 1999    Pfizer Inc.   “Detection of adverse events in clinical trial data”
1998 -- 1999    NIH/NHLBI   "Informatics for the National Heart Attack Alert program"
1999 –current  DARPA    “High-Performance Knowledge Bases Project“ 
 1999 -- 2000   NLM    “MAITA Project”
 

Postdoctoral Training
 1995-1999 Research/Clinical Fellow,  New England Medical Center, Boston
 1992-1995  Career Registrar in Cardiology,  Edinburgh Royal Infirmary and Falkirk and District Royal Infirmary, UK
 1992 6/12 Locum Registrar in Cardiology,   The Freeman Hospital, Newcastle, UK 
 1989-1990 Senior House Officer in Medicine, Northern General Hospital, Sheffield, UK. 
 1988-1989  Senior House Officer in Medicine, Stirling Royal Infirmary, Stirling, UK. 
 1987-1988  Senior House Officer in Medicine, Falkirk and District Royal Infirmary, UK 
 1986-1987 Internship,    Western General Hospital, and  The Royal Infirmary, Edinburgh, UK
 

 R.L. Kennedy, A.M. Burton, H.S. Fraser, L.N. McStay, R.F. Harrison 
 Early Diagnosis of Acute Myocardial Infarction Using Clinical and Electrocardiographic Data at Presentation: Derivation and Evaluation of Logistic Regression Models 
 European Heart Journal, Vol. 17, August 1996, p1181 – 91

William J. Long, Hamish Fraser, Shapur Naimi
 A Web Interface for the Heart Disease Program
 AMIA Fall Symposium, 1996, October ; Washington, DC. Hanley and Belfus; 1996. p. 762-6

 Kennedy RL, Harrison RF, Burton AM, Fraser HS, Hamer WG, MacArthur D, McAllum R,
 Steedman DJ,An Artificial Neural Network System For Diagnosis Of Acute Myocardial Infarction (AMI) In The Accident   And Emergency Department: Evaluation And Comparison With Serum Myoglobin Measurements.
 Comput Methods Programs Biomed 1997 Feb;52(2):93-103

 Hamish S F Fraser, Isaac S Kohane, William J Long. 
 Using the Technology of the World Wide Web to Manage Clinical Information 
 British Medical Journal, No 7094 Volume 314 Saturday 31 May 1997 P 1600-4
 http://www.bmj.com/archive/7094ip1.htm

W. J. Long, H. Fraser, and S. Naimi, 
Reasoning Requirements for Diagnosis of Heart Disease. Artificial Intelligence in Medicine 10 (1997) pp. 5 – 24

Milos Hauskrecht, Hamish Fraser
 Planning Medical Therapy Using Partially Observable Markov Decision Processes
 Dx98, Cape Cod, May 1998

 Christine L Tsien, Hamish S F Fraser, William J Long, R Lee Kennedy 
 Using Classification Tree and Logistic Regression Methods to Diagnose Myocardial Infarction
 MEDINFO 98, Seoul, Korea, August 1998; Pt 1:493-7.

 Tsien CL, Fraser HS, Kohane IS.
 LRTree: a hybrid technique for classifying myocardial infarction data containing unknown attribute values. 
 Research and Development in Knowledge Discovery and Data Mining.  Wu X, Kotagiri R, Korb KB, eds., Lecture Notes in Artificial Intelligence 1394.  Berlin Heidelberg: Springer-Verlag 1998: 409-411. 

 Hamish S F Fraser, William J Long, Shapur Naimi.
 Differential Diagnoses of the Heart Disease Program have better Sensitivity than Resident Physicians.
 AMIA Fall Symposium on Computer Applications in Health Care, 1998 November 7-11. Orlando, Florida; Hanley and Belfus; 1998, p 622-26

 Milos Hauskrecht, Hamish Fraser
 Modelling Treatment of Ischemic Heart Disease with Partially Observable Markov Decision Processes. 
 AMIA Fall Symposium on Computer Applications in Health Care, 1998 November 7-11. Orlando, Florida; Hanley and Belfus; 1998, p 538-42

 L. Ohno-Machado, H.S. Fraser, A. Ohrn
 Improving Machine Learning Performance by Removing Redundant Cases in Medical Data Sets 
 AMIA Fall Symposium on Computer Applications in Health Care, 1998 November 7-11. Orlando, Florida; Hanley and Belfus; 1998, p 523-27

 Milos Hauskrecht, Hamish Fraser
 Modelling Treatment of Ischemic Heart Disease with Partially Observable Markov Decision Processes. 
 AMIA Fall Symposium on Computer Applications in Health Care, 1998 November 7-11. Orlando, Florida; Hanley and Belfus; 1998, p 538-42

 L. Ohno-Machado, H.S. Fraser, A. Ohrn
 Improving Machine Learning Performance by Removing Redundant Cases in Medical Data Sets 
 AMIA Fall Symposium on Computer Applications in Health Care, 1998 November 7-11. Orlando, Florida; Hanley and Belfus; 1998, p 523-27

 M. Hauskrecht, H. Fraser. Planning treatment of ischemic heart disease with
 partially observable Markov decision processes. 
 Artificial Intelligence in Medicine, vol. 18, pp. 221-244, 2000

 Wang SJ, Ohno-Machado L, Fraser HS, Kennedy RL.
 Using Patient-Reportable Clinical History Factors to Predict Myocardial Infarction
 Comput Biol Med. 2001 Jan 1;31(1):1-13.

 Hamish S F Fraser, William J Long, Shapur Naimi
 New Approaches to Measuring the Performance of Programs that Generate Differential Diagnoses using ROC Curves and Other Metrics.
 Proc AMIA Symp. 2000;:255-9.

Fraser HS, Jazayeri D, Bannach L, Szolovits P, McGrath SJ.
Telemedmail: free software to facilitate telemedicine in developing countries.
Medinfo. 2001;10(Pt 1):815-9. 

Lober WB, Thomas Karras B, Wagner MM, Marc Overhage J, Davidson AJ, Fraser H, Trigg LJ, Mandl KD, Espino JU, Tsui FC.
Roundtable on Bioterrorism Detection: Information System-based Surveillance.
J Am Med Inform Assoc. 2002 Mar-Apr;9(2):105-15.

Hamish SF Fraser
Clinical information and decision-support systems
Chapter 3.2, Medicine and the Internet (Third Edition)
Bruce McKenzie Editor
Oxford University Press 2002