Logo

Modified: Feb, 2007

This site is no longer up-to-date. Please go to http://compbio.med.harvard.edu


We are a bioinformatics research group and are part of Children's Hospital Informatics Program, Harvard-Partners Center for Genomics and Genetics, and Harvard-MIT Division of Health, Science, & Technology.

News:

* July 2007: A big welcome to the three new members of the group: Hyunsoo Kim, Michael Tolstorukov, and Vidhu Choudary!

* Sep, 2006. We are part of the Cancer Genome Atlas Project team at Harvard Medical School and Brigham and Women's Hospital. This team will characterize tumor samples for alterations in chromosome segments copy number and will also develop new technologies to analyze expression profiles.

"Biologists can be divided into two classes: experimentalists who observe things that cannot be explained, and theoreticians who explain things that cannot be observed." --A. Katzir-Katchalsky, as quoted by G.F.Oster."

Introduction

Recent technological developments have enabled researchers to generate experimental data in an unprecedented, genome-wide scale. Our aim is to gain biological insights through computational and statistical analysis of genomic data.

Integrative analysis of genomic data

Methodological work: We develop new statistical and computational algorithms and tools for understanding a variety of data types, such as gene expression, array comparative genomics hybridization, and Chromatin Immunoprecipitation/microarray (ChIP-chip). We are particularly interested methods for combining heterogeneous data sets to derive new insights. Our goal is to address important problems and come up with efficient and statistically valid methods that will have practical impact on biological and clinical investigators.

Collaborative work: We work closely with several basic and clinical research groups. We strive to maintain a close and synergistic relationship through which we can address important biological and methdological problems effectively.

 

Open Positions (New, Feb 2007):

Postdoctoral Fellowship:

Applications are invited for two postdoctoral positions in bioinformatics, available immediately. Please send a cover letter, a CV, and pdfs of your recent papers to peter_park at harvard dot edu. Applicants with strong background in applied/computational mathematics, computer science, or statistics are preferred but there are no formal requirements. The successful candidate would work on development of new methods for understanding large biological datasets including gene expression, chromatin modifications, and protein interactions as well as on collaborative projects.

Scientific Programmer:

Applications are invited for a position in software development. A bachelor's degree in computer science or a related field is required. The primary object is to design web-based software that implement algorithms developed by the members of the group. Experience in web programming (CGI, Perl, mysql, etc) and familiarity with various platforms would be ideal. The individual will have a chance to develop important tools that enable medical researchers to interpret their genomic datasets. The person will be funded by the National Center for Biomedical Computing grant recently awarded at Harvard.

Undergraduate Research Assistants (MIT UROP or Harvard):

Multiple positions are open for undergraduates throughout the year. A 10-hour commitment during the term and full-time commitment during summer are required. Strong quantitative background and substantial programming experience are essential. Underclassmen with such experience are welcome to apply. You may also be interested in the Summer Institute in Bioinformatics and Integrative Genomics at Harvard-MIT Health, Science and Technology.